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20th Conference on Retroviruses and Opportunistic Infections (CROI 2013)

March 3-6, 2013, Atlanta

CROI 2013: Gene Therapy Studies Show Potential for HIV Control without Drugs

Modified immune cells that make their own fusion inhibitors reduce levels of HIV-like virus and resisted infection in animal and test tube studies, researchers reported at the 20th Conference on Retroviruses and Opportunistic Infections (CROI 2013) last month in Atlanta.

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CROI 2013: Growing Number of HIV+ New Yorkers Achieve Viral Load Suppression [VIDEO]

Expanded testing, earlier treatment, and better engagement in care has led to more people with HIV in New York City achieving and maintaining undetectable viral load, according to study findings presented at the 20th Conference on Retroviruses and Opportunistic Infections (CROI 2013) last month in Atlanta.

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CROI 2013: Telaprevir Triple Therapy Improves HCV Response for Black Null Responders

Adding the HCV protease inhibitor telaprevir (Incivek) to pegylated interferon and ribavirin increased end-of-treatment response rates for difficult-to-treat patients including African-Americans who previously did not respond to interferon, according to study results presented at the recent 20th Conference on Retroviruses and Opportunistic Infections (CROI 2013)in Atlanta.

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CROI 2013: Antiretroviral Therapy Intensification plus IL-7 Does Not Reduce HIV Reservoir

 An intensive antiretroviral regimen containing raltegravir (Isentress) and maraviroc (Selzentry) plus the immune-modulator interleukin 7 (IL-7) was unable to decrease the amount of residual HIV in resting CD4 T-cells, investigators with the ERAMUNE-01 trial reported at the recent 20th Conference on Retroviruses and Opportunistic Infections (CROI 2013) in Atlanta.

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French Cohort of HIV+ People Treated Early Appear to Control Virus

A group of French HIV patients who started antiretroviral therapy (ART) during the earliest stage of infection appear to be controlling the virus despite prolonged treatment interruption, according to a recent report in PLoS Pathogens. While the findings do not represent a cure, they may offer insight to help certain people with HIV achieve a "functional cure," or periods off treatment without disease progression.

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