Hepatitis B Topics HBV Disease Progression
AASLD 2011: Engineered Poxvirus Shows Promise for Treating Advanced Liver Cancer
- Details
- Category: Liver Cancer/HCC
- Published on Tuesday, 08 November 2011 00:00
- Written by Jennerex
A genetically engineered vaccinia poxvirus (JX-594) can rapidly destroy tumors and prolong survival of people with advanced hepatocellular carcinoma (HCC), according to a late-breaker presentation at the American Association for the Study of Liver Diseases Liver Meeting (AASLD 2011) this week in San Francisco.
Changes Proposed for Allocation of Donated Livers
- Details
- Category: Liver Transplant - HBV
- Published on Thursday, 01 September 2011 00:00
- Written by Wiley-Blackwell
For some patients transplantation is the only treatment for advanced liver disease due to chronic hepatitis B, hepatitis C, liver cancer, alcoholism, or other causes. But the supply of donor livers does not meet the demand, meaning that many people die while on a waiting list. As described in the September 2011 issue of Liver Transplantation, experts have been meeting for the past 2 years to develop a modified allocation system that aims to reduce wait-list mortality.
Deferoxamine Shows Promise for Liver Cancer in People with Advanced Disease
- Details
- Category: Liver Cancer/HCC
- Published on Friday, 12 August 2011 00:00
- Written by Liz Highleyman
Deferoxamine, a cancer drug that has an anti-proliferative effect on tumor cells, led to improvement of hepatocellular carcinoma (HCC) in 2 out of 10 patients with moderate-to-severe liver disease, according to a letter in the August 11, 2011, New England Journal of Medicine.
Hepatitis Delta Found in 15% of HIV/HBV Coinfected People, Increases Risk of Death
- Details
- Category: Hepatitis Delta (HDV)
- Published on Thursday, 01 September 2011 00:00
- Written by Liz Highleyman
Approximately 15% of people with HIV who test positive for hepatitis B surface antigen (HBsAg) also carry hepatitis delta virus (HDV), a defective virus that can only replicate in the presence of hepatitis B virus (HBV) but can lead to more severe liver damage, according to a recent European study.
One-quarter of Patients Clear Hepatitis Delta with Pegylated Interferon
- Details
- Category: Hepatitis Delta (HDV)
- Published on Friday, 28 January 2011 03:30
- Written by HIVandHepatitis.com
Treatment with pegylated interferon (Pegasys) -- either alone or in combination with the antiviral drug adefovir (Hepsera) -- led to clearance of hepatitis delta virus (HDV) and improvement in liver enzyme levels, according to a small study published in the January 27, 2011, New England Journal of Medicine. Adefovir alone, however, had no effect on HDV.
High HBV Viral Load Predicts Liver Fibrosis and Cancer
- Details
- Category: HBV Disease Progression
- Published on Tuesday, 30 August 2011 00:00
- Written by Liz Highleyman
High hepatitis B virus (HBV) DNA levels were associated with worse liver fibrosis, hepatitis reactivation, and development of hepatocellular carcinoma (HCC) in hepatitis B "e" antigen (HBeAg) negative patients in 2 recent studies described in the July 2011 Journal of Viral Hepatitis.
Does Previous Hepatitis B Exposure Increase Liver Cancer Risk?
- Details
- Category: Liver Cancer/HCC
- Published on Tuesday, 14 December 2010 12:48
- Written by Liz Highleyman
People who were previously exposed to hepatitis B virus (HBV) have an increased likelihood of developing hepatocellular carcinoma (HCC) even if they clear the virus, according to a study presented at the recent American Association for the Study of Liver Diseases "Liver Meeting" (AASLD 2010) in Boston. These results suggest that individuals with prior HBV exposure, as well as those with chronic hepatitis B, could benefit from regular liver cancer monitoring.Jeffrey Tang and colleagues from Henry Ford Health System in Detroit conducted a retrospective cohort study to explore the association between hepatitis B serologic status and development of HCC among North American patients.
More Articles...
- Artificial Liver Device Improves Survival for Hepatitis B and C Patients with Decompensated Disease
- Alcohol and Diabetes Increase Risk of Liver Disease Progression in Hepatitis B Patients
- Androgen Receptor May Explain Why More Men with Hepatitis B Develop Liver Cancer
- Sex Hormone Receptor May Explain Higher Risk of Hepatocellular Carcinoma in Men
- EASL 2010: Measurable Neurocognitive Impairment Persists after Episodes of Hepatic Encephalopathy in People with Liver Cirrhosis
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