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U.S. Approves New Hepatitis B Vaccine as Public Health Agencies Update Guidelines

On November 9 the U.S. Food and Drug Administration(FDA) approved Heplisav-B, a new vaccine that provides protection against all known subtypes of hepatitis B virus (HBV) with 2 rather than 3 doses, which is expected to reduce the number of people who do not complete the vaccine series.

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PAS 2017: Children on Immunosuppressive Therapy May Lose Hepatitis B Vaccine Protection

More than half of children treated with immunosuppressive drugs for gastrointestinal or rheumatological conditions no longer had protective levels of antibodies against hepatitis B virus (HBV) and may require repeat vaccinations, according to a study presented at the Pediatric Academic Societies Meeting last week in San Francisco.

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HIV Controllers Respond Better to Hepatitis B Vaccine

HIV positive natural controllers who maintain undetectable or low viral load without antiretroviral therapy (ART) are more likely to achieve adequate response to hepatitis B virus (HBV) vaccination and have improved survival, according to a study published in the August 21 edition of the open-access journal PLoS ONE.

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Telbivudine Prevents Mother-to-Child Hepatitis B Virus Transmission

Women with a high hepatitis B viral load who were treated with the antiviral drug telbivudine (Tyzeka) had a lower risk of transmitting the virus to their babies during pregnancy or birth -- in fact, none did so -- compared to untreated women whose infants only received standard immunoprophylaxis, according to a Chinese study reported in the June edition of Clinical Gastroenterology and Hepatology.

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EASL 2014: Sci-B-Vac Bests Engerix-B for Preventing Mother-to-Child HBV Transmission

An investigational vaccine known as Sci-B-Vac given to babies born to women with hepatitis B was more effective at preventing HBV infection than the widely used Engerix-B vaccine, according to a report at the EASL International Liver Congress this month in London.

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EASL 2015: Expanded Vaccination and Treatment Could Help Eliminate Hepatitis B Worldwide

While universal infant hepatitis B virus (HBV) vaccination has already led to major advances in reducing new infections in some settings, further expansion of prevention and treatment are needed to significantly reduce HBV transmission and liver disease mortality, according to an analysis presented at the European Association for the Study of the Liver (EASL) 50th International Liver Congress this week in Vienna.

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CDC Updates Guidance for Hepatitis B Vaccination of Health-care Providers

The U.S. Centers for Disease Control and Prevention (CDC) has published updated guidance for evaluating and ensuring protection against hepatitis B virus (HBV) for health-care workers, as well as post-exposure prophylaxis recommendations for those without adequate vaccine protection.

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