Vitamin D Linked to HIV Disease Progression
- Details
- Category: Alternative & Complementary Therapy
- Published on Tuesday, 17 May 2011 05:08
- Written by HIVandHepatitis.com
EuroSIDA researchers found that more than 80% of HIV positive people on antiretroviral therapy (ART) had vitamin D deficiency, which was associated with higher risk of AIDS-related illness and death.
Discordant Responders Do Well If Viral Load Remains Suppressed
- Details
- Category: HIV Treatment
- Published on Friday, 21 January 2011 23:40
- Written by Liz Highleyman
HIV positive people with advanced immune deficiency are unlikely to progress to AIDS after 6 months on antiretroviral therapy as long as they maintain an undetectable viral load, even if they have trouble achieving substantial CD4 cell recovery, according to new research published in the February 1, 2011, Journal of Infectious Diseases. These findings suggests that HIV patients and their clinicians should prioritize viral suppression and do not necessarily need to change drugs due to lagging immunological response.
Small Difference in Physical Function between Older HIV Positive and Negative People
- Details
- Category: HIV Disease Progression
- Published on Friday, 14 January 2011 12:55
- Written by Liz Highleyman
Aging HIV positive U.S. veterans had slightly but significantly worse physical function than their HIV negative counterparts, and experienced greater yearly declines, according to study findings reported in the January 2011 issue of AIDS Patient Care and STDs. Differences diminished, however, after controlling for confounding factors such as injection drug use and hepatitis C coinfection, and when comparing people with specific diseases.
Cell Marker Linked to Poor Immune Recovery on Antiretroviral Therapy
- Details
- Category: HIV Treatment
- Published on Friday, 21 January 2011 12:55
- Written by Liz Highleyman
A cell surface protein known as PD-1 (a marker of cell apoptosis, or programmed death) is expressed at higher levels in HIV positive individuals who experience slow CD4 T-cell recovery after starting antiretroviral therapy, according to an Austrian study described in the February 1, 2011, Journal of Acquired Immune Deficiency Syndromes. This increase in PD-1 expression appeared distinct from overall T-cell activation or immune system exhaustion due to age.
Untreated Individuals Show Increased HIV in Cells despite Stable Plasma Viral Load
- Details
- Category: HIV Disease Progression
- Published on Friday, 03 September 2010 14:17
- Written by Liz Highleyman
The amount of viral genetic material in peripheral blood immune cells rises steadily over time in HIV positive people who are not taking antiretroviral therapy (ART), according to Dutch study described in the July 17, 2010 issue of AIDS. HIV levels in these cells increased even if blood plasma viral load remained stable, and was associated with decreases in CD4 cell count.
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- CROI 2010: Even Low-level, Short-term Detectable Viral Load Raises the Risk of Virological Treatment Failure and Death
- CROI 2009: ESPRIT and SILCAAT Studies Find No Long-term Benefits of IL-2