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HIV Disease Progression

CROI 2012: U.S. Black Women Have Higher Rates of HIV Infection and AIDS Death

Urban black women in the U.S. are 5 times more likely to become infected with HIV than previously estimated, and are twice as likely to die of AIDS-related causes, according to 2 posters presented this month at the 19th Conference on Retroviruses and Opportunistic Infections (CROI 2012) in Seattle.alt

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Are HIV Non-Progressors Really Very Slow Progressors?

HIV positive people traditionally classified as long-term non-progressors or viral controllers may in fact progress slowly over time, according to research reported in the February 20, 2012, edition of the open-access journal PLoS ONE. These findings suggest that so-called altnon-progressors may in fact benefit from antiretroviral therapy and could provide clues to aid in development of immune-based therapies. 

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Cumulative Viral Load Predicts Mortality for Untreated People with HIV

"Viremia copy-years," or cumulative HIV viral load over time, was a good predictor of deaths due to all causes among people on combination antiretroviral therapy (ART), independent of cross-sectional, or one-time, viral load measurements or CD4 T-cell counts, researchers reported in the September 2, 2011, advance online edition of Clinical Infectious Diseases.alt

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Low but Detectable Viral Load Can Lead to HIV Rebound

People with HIV RNA levels < 50 copies/mL but detectable may still experience viral rebound while on antiretroviral therapy, and should consider switching to a more effective regimen if low-level viral load persists, according to a study described in the January 11, 2012, advance online edition of Clinical Infectious Diseases.alt

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Increased Risk of Death for HIV+ People Mostly Due to Modifiable Risk Factors

Elevated mortality among people with HIV is largely attributable to risk factors that are modifiable before or during antiretroviral therapy (ART), according to the latest findings from the Danish HIV cohort published in the July 25, 2011, online edition of PLoS Medicine.alt

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