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Children & Adolescents

IAS 2013: New WHO Guidelines on HIV Treatment for Children Require Earlier Diagnosis

New World Health Organization (WHO) guidelines recommending antiretroviral treatment for all children with HIV under the age of 5, and treatment for all older children and adolescents with CD4 counts below 500 cells/mm3, will need to be backed up by efforts to greatly improve early infant diagnosis, together with development of easier-to-take antiretrovirals for children, pediatric experts told the 7th International AIDS Society conference (IAS 2013) on Monday.

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UNAIDS: HIV Infections among Children Drop by Half in African Countries

New HIV infections among children by fallen by at least 50% since 2009 in 7 high-prevalence countries in sub-Saharan Africa, largely due to improvements in preventing mother-to-child transmission, according to a Global Plan progress report issued this week by UNAIDS.

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FDA Approves Efavirenz (Sustiva) for HIV+ Children Ages 3 Months to 3 Years

The U.S. Food and Drug Administration (FDA) announced on May 3 that it has approved a supplemental new drug application for use of efavirenz (Sustiva) by infants and young children with HIV. The new dosing recommendation includes the option to sprinkling capsule contents on food for children who are unable to swallow pills.

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Efavirenz More Effective than Nevirapine for Children with HIV

HIV positive African children and adolescents treated with efavirenz (Sustiva) were less likely to experience virological failure than those using nevirapine (Viramune), according to a large comparative study published in the May 1, 2013, Journal of the American Medical Association. Nevirapine, however, is less expensive and more widely available for children in low-income countries.

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Antiretroviral Therapy May Have Protective Effect on HIV+ Children's Hearts

Long-term use of combination antiretroviral therapy (ART) does not impair heart function in children and adolescents with perinatal HIV infection, and in fact appears to have a "cardioprotective" effect, according to a study published in the April 22, 2013, advance online edition of JAMA Pediatrics.

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