Microbicides
Microbicides
New NRTI Microbicide Looks Promising in Lab
- Details
- Category: Microbicides
- Published on Thursday, 05 May 2011 17:49
- Written by Liz Highleyman
A novel vaginal microbicide gel containing the reverse transcriptase inhibitor IQP-0528 demonstrated good antiviral activity and safety in laboratory studies.
CROI 2011: Safety and Acceptability of Tenofovir Gel and Tablets for Pre-exposure Prevention
- Details
- Category: HIV Prevention
- Published on Friday, 04 March 2011 00:00
- Written by Paul Dalton
A vaginal microbicide gel containing tenofovir was found to be generally well tolerated and acceptable by American and African women, though some study participants preferred taking a pill for HIV pre-exposure prophylaxis (PrEP), according to study findings reported this week at the 18th Conference on Retroviruses and Opportunistic Infections (CROI 2011) in Boston. A related study found that the vaginal gel was not suitable for rectal use, and researchers are working on a more tolerable formulation.
CAPRISA Microbicide Trial Shows Tenofovir Vaginal Gel Reduces HIV Transmission Risk by 39%
- Details
- Category: HIV Prevention
- Published on Tuesday, 20 July 2010 13:56
- Written by Liz Highleyman
An antiretroviral vaginal gel containing tenofovir offered women moderate protection against HIV infection when administered before and after sex, according to findings from the CAPRISA 004 trial published in the July 19, 2010 issue of Science and announced at the XVIII International AIDS Conference (AIDS 2010).
FDA Grants Fast-track Status for Tenofovir Microbicide Gel for HIV Prevention
- Details
- Category: Microbicides
- Published on Tuesday, 02 November 2010 14:17
- Written by CONRAD
CONRAD, an agency spearheading research on microbicides to help prevent sexual transmission of HIV, last week announced that the U.S. Food and Drug Administration (FDA) has granted "fast track" status to enable quicker review of studies looking at 1% tenofovir gel, which reduced women's risk of HIV infection by 39% in the Phase 2 CAPRISA trial that garnered worldwide headlines at the International AIDS Conference (AIDS 2010) this summer in Vienna.
Green Tea Compound in a Microbicide May Help Prevent HIV Entry into Cells
- Details
- Category: Microbicides
- Published on Tuesday, 16 June 2009 14:12
- Written by Liz Highleyman
Since the start of the AIDS epidemic, researchers have sought women-controlled HIV prevention methods such as microbicide gels to reduce the risk of infection during sex. A wide variety of natural and manufactured chemicals have been tested as potential microbicides. Now, scientists report that a compound in green tea may help prevent HIV from attacking cells via semen.
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