Neurocognitive Problems
AIDS 2010: CHARTER Study Finds Neurocognitive Impairment Still Common in ART Era, Linked to Lowest CD4 Cell Count
- Details
- Category: Neurocognitive Problems
- Published on Friday, 06 August 2010 13:56
- Written by Liz Highleyman
Neurocognitive impairment ranging from subtle to severe remains common among people with HIV despite widespread use of effective combination antiretroviral therapy (ART), according to findings from the large CHARTER study presented at the XVIII International AIDS Conference (AIDS 2010) last month in Vienna. Impairment was associated with nadir or lowest-ever CD4 cell count, even among individuals whose immune function has since recovered on ART.
Can Morphine Help Protect the Brain against HIV Neurotoxicity and Cognitive Impairment?
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- Category: Neurocognitive Problems
- Published on Tuesday, 20 April 2010 14:16
- Written by Georgetown University Medical Center
Morphine, a drug derived from opium poppies that relieves pain and often triggers addiction, may help protect the brain from damage due to HIV by interfering with the virus' ability to enter cells, according to a study in mice reported last week at the annual meeting of the Society of NeuroImmune Pharmacology. The researchers emphasized that people should not use morphine or similar drugs like heroin to protect the brain, but suggested these findings may offer clues for designing future therapies to prevent neurocognitive impairment in people with HIV.
CROI 2010: HIV/HCV Coinfected Patients Demonstrate Poorer Neurocognitive Performance, but No Difference in Neural Imaging
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- Category: Neurocognitive Problems
- Published on Tuesday, 06 April 2010 13:57
- Written by Liz Highleyman
HIV/HCV coinfected individuals with good HIV suppression on performed more poorly than HIV monoinfected people on neurocognitive tests, but the 2 groups showed no significant differences in neural imaging measures, according to a study presented at the recent 17th Conference on Retroviruses and Opportunistic Infections in San Francisco (CROI 2010).
CROI 2010: Risk Factors for Neurocognitive Impairment among People with HIV
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- Category: Neurocognitive Problems
- Published on Tuesday, 06 April 2010 13:57
- Written by Liz Highleyman
People with higher blood and cerebrospinal fluid viral load and lower CD4 cell count are more likely to develop neurocognitive impairment, according to studies presented in February at the 17th Conference on Retroviruses and Opportunistic Infections (CROI 2010) in San Francisco. In addition, researchers with the SMART study reported that cardiovascular risk factors predict poorer neurocognitive performance. But conflicting findings emphasize the need for further research.
Acute Hepatitis C Affects Neurocognitive Functioning in People with HIV
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- Category: Neurocognitive Problems
- Published on Friday, 22 May 2009 13:47
- Written by Liz Highleyman
Acute coinfection with hepatitis C virus (HCV) can contribute to neurocognitive impairment in people with HIV, according to a British study presented at the 44th Annual Meeting of the European Association for the Study of the Liver (EASL 2009) last month in Copenhagen.