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HIV-Related Conditions

IAS 2011: People with HIV Have Double Risk for Non-Melanoma Skin Cancers

Details: Category: Cancer/Malignancies; Published on Tuesday, 02 August 2011 00:00; Written by Liz Highleyman

Several studies conducted in the era of effective antiretroviral therapy (ART) have shown that people with HIV have higher rates of non-AIDS-defining cancers, especially those caused by infectious pathogens such as human papillomavirus or hepatitis B or C. alt

IAS 2011: Doubt Remains if HIV Therapy Increases the Risk of Fragility Fractures

Details: Category: Bone Loss; Published on Tuesday, 26 July 2011 00:00; Written by Michael Carter

The relationship between HIV therapy and fracture risk is far from straightforward, U.S. research presented to the International AIDS Society conference in Rome suggests.

Liver Fibrosis Common in HIV+ People without Viral Hepatitis

Details: Category: Liver & Kidney Disease; Published on Monday, 02 May 2011 18:09; Written by Liz Highleyman

Non-invasive blood tests indicate that people with HIV have a significant risk of liver fibrosis progression even if they do not have hepatitis B or C coinfection.

IAS 2011: Cognitive Impairment is Common, but ART Reduces Risk

Details: Category: Neurocognitive Problems; Published on Wednesday, 20 July 2011 00:00; Written by Liz Highleyman

Cognitive impairment remains common among people with HIV and is linked to more severe immune deficiency and absence of treatment, researchers reported at the International AIDS Society Conference on HIV Pathogenesis, Treatment and Prevention (IAS 2011) this week in Rome. But drugs that penetrate the central nervous system do not appear to improve overall outcomes. alt

HIV Linked to Increased Heart Failure Risk

Details: Category: Cardiovascular Disease; Published on Thursday, 28 April 2011 18:38; Written by Paul Dalton

People with HIV, especially those with detectable viral load, were found to be at increased risk of heart failure in a study of U.S. veterans.

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IAS 2011: Coronary Artery Calcification Linked to Bone Loss

Details: Category: Cardiovascular Disease; Published on Tuesday, 19 July 2011 00:00; Written by Paul Dalton

Coronary artery calcification is associated with and low femoral bone mineral density (BMD), but no such link found with lumbar spine BMD, researchers reported at IAS 2011 in Rome.

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People with AIDS Account for Fewer U.S. Cancer Cases

Details: Category: Cancer/Malignancies; Published on Monday, 25 April 2011 21:44; Written by Paul Dalton

People with AIDS are now contributing proportionately less to total cancer cases in the U.S.

IAS 2011: Transplants Safe for HIV+ People but HCV Adds Risk

Details: Category: Liver & Kidney Disease; Published on Monday, 18 July 2011 00:00; Written by Paul Dalton

Kidney and Liver transplants can be safe and effective for people living with HIV. However hepatitis C virus (HCV) coinfection and several other factors may make such procedures more risky. alt

More Evidence Abacavir Does Not Raise Heart Attack Risk

Details: Category: Cardiovascular Disease; Published on Monday, 18 April 2011 22:25; Written by Paul Dalton

A large cohort study found no increased risk of myocardial infarction in people taking abacavir.

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Damage to Blood-Brain Barrier May Explain Neurocognitive Problems

Details: Category: Neurocognitive Problems; Published on Friday, 08 July 2011 11:12; Written by Matt Sharp

HIV weakens the blood-brain barrier, which may help explain low-level cognitive impairment in people with HIV despite effective antiretroviral treatment.

Non-AIDS Cancers Increasing in People with HIV

Details: Category: Cancer/Malignancies; Published on Thursday, 14 April 2011 22:58; Written by Liz Highleyman

AIDS-related cancers are now less common, but people with HIV are at higher risk for some non-AIDS cancers, especially those linked to infectious viruses.

Lowest-ever CD4 Count Predicts Cognitive Impairment

Details: Category: Neurocognitive Problems; Published on Friday, 08 July 2011 11:00; Written by Liz Highleyman

Low nadir CD4 T-cell count before starting antiretroviral treatment raises risk of neurocognitive problems for people with HIV.

CROI 2011: HIV/HCV Coinfected People Have Higher Risk of Bone Loss

Details: Category: Bone Loss; Published on Tuesday, 05 April 2011 15:11; Written by Liz Highleyman

People with both HIV and hepatitis C are more likely to sustain hip or spine fractures than people with one or none of these viruses, according to a study of nearly 39,000 Medicaid recipients presented at CROI 2011. alt

Triglycerides Contribute to Higher HIV+ Heart Attack

Details: Category: Cardiovascular Disease; Published on Friday, 17 June 2011 02:32; Written by Liz Highleyman

Higher triglycerides were marginally associated with increased risk of myocardial infarction in the large D:A:D trial, but the effect was small after taking into account cholesterol and other cardiovascular disease risk factors.

CROI 2011: HIV Enters and Injures Brain Early

Details: Category: Neurocognitive Problems; Published on Tuesday, 29 March 2011 00:32; Written by Paul Dalton

Structure and function changes in the brain are evident early in the course of HIV infection and are linked to inflammation, researchers reported at CROI 2011.

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Do HIV+ People Have Higher Stroke Risk?

Details: Category: Cardiovascular Disease; Published on Tuesday, 14 June 2011 02:53; Written by Liz Highleyman

A Danish study finds HIV positive people have a higher risk for stroke, increasing with injection drug use and lower CD4 cell count but not antiretroviral therapy overall.

CROI 2011: Studies Shed Further Light on Cardiovascular Disease among People with HIV

Details: Category: Cardiovascular Disease; Published on Friday, 18 March 2011 00:00; Written by Paul Dalton

HIV positive people are at higher risk for cardiovascular disease overall, compared with HIV negative individuals, according to findings from Kaiser Permanente presented this month at the 18th Conference on Retroviruses and Opportunistic Infections (CROI 2011). Other studies found that HIV positive people on ART with well-preserved immune function were not at greater risk, however, and that abacavir (Ziagen) was not linked to heart attacks.

Niaspan + Statin Does Not Reduce Heart Attack Risk

Details: Category: Cardiovascular Disease; Published on Tuesday, 31 May 2011 00:31; Written by NIH

The large AIM-HIGH trial showed that extended-release niacin (Niaspan) plus simvastatin (Zocor) raised HDL cholesterol and lowered triglycerides, but the combo did not decrease the likelihood of heart attacks and may have increased the risk of strokes.

CROI 2011: FDA Safety Review Does Not Find Abacavir-Heart Attack Link

Details: Category: Cardiovascular Disease; Published on Friday, 04 March 2011 08:56; Written by FDA

A meta-analysis by researchers from the U.S. Food and Drug Administration (FDA) adds to the ongoing debate about the association between the NRTI abacavir (Zaigen, also in the Epzicom and Trizivir coformulations) and increased risk of myocardial infarction and other cardiovascular events. The new review of 26 randomized clinical trials, presented as a poster at the 18th Conference on Retroviruses and Opportunistic Infections (CROI 2011) this week in Boston, did not reveal a significant link between abacavir and heart attacks.

Low CD4 Count Linked to Bone Fractures

Details: Category: Bone Loss; Published on Tuesday, 10 May 2011 04:38; Written by Liz Highleyman

A large Australian study found HIV positive people with lower CD4 T-cell counts were at greater risk of fractures due to bone loss. alt

Risk of Strokes Is Increasing for People with HIV

Details: Category: Cardiovascular Disease; Published on Friday, 28 January 2011 12:55; Written by Liz Highleyman

The number of HIV positive people hospitalized due to ischemic strokes -- the type caused by blocked blood flow to the brain -- increased by 60% over the past decade, even as the number fell among the U.S. population at large, according to research described in the January 19, 2011, advance online issue of Neurology. Even after accounting for the larger number of people living with HIV, stroke risk increased by about 40% since 2001.

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