Search for a Cure
Search for a Cure
CROI 2016: VRC01 Antibody Delays But Does Not Prevent HIV Rebound After ART Interruption
- Details
- Category: Search for a Cure
- Published on Thursday, 31 March 2016 00:00
- Written by Liz Highleyman
VRC01, a broadly neutralizing antibody targeting HIV's CD4 binding site, was able to modestly delay the return of viral replication following interruption of antiviral therapy (ART), according to a study presented at the Conference on Retroviruses and Opportunistic Infections (CROI 2016)last month in Boston. VRC01 did not maintain viral suppression on its own, but it may play a role in combination therapy for HIV treatment or a functional cure.
CROI 2016: Dose-Finding Trials of Antibody-Based Drugs for HIV Prevention To Start Soon
- Details
- Category: Search for a Cure
- Published on Wednesday, 30 March 2016 00:00
- Written by Gus Cairns
The next generation of pre-exposure prophylaxis (PrEP), and even HIV treatment, may consist of antibodies that could be given as an intravenous infusion or an injection into muscle, according to 2 presenters at the Conference on Retroviruses and Opportunistic Infections (CROI 2016)last month in Boston.
Coverage of the 2016 Conference on Retroviruses and Opportunistic Infections
- Details
- Category: HIV Treatment
- Published on Friday, 26 February 2016 00:00
- Written by HIVandHepatitis.com
HIVandHepatitis.com coverage of the 2016 Conference on Retroviruses and Opportunistic infections (CROI 2016), February 22-25, 2016, in Boston.
HIVandHepatitis.com coverage by topic
2/26/16
CROI 2016: Experimental TLR7 Agonist Suppresses HIV-Like Virus in Monkeys After ART Interruption
- Details
- Category: Search for a Cure
- Published on Monday, 29 February 2016 00:00
- Written by Liz Highleyman
GS-9620, an investigational toll-like receptor or TLR7 agonist, led to immune activation in a study of macaque monkeys infected with an HIV-like virus, and 2 of the animals treated with multiple doses have maintained viral suppression for at least 3 months after stopping antiretroviral treatment, according to research presented at the Conference on Retroviruses and Opportunistic Infections (CROI 2016) last week in Boston.
Study Sheds Light on Ongoing HIV Replication in Lymph Node Reservoirs
- Details
- Category: Search for a Cure
- Published on Friday, 29 January 2016 00:00
- Written by Northwestern University
HIV may continue to replicate in sanctuary sites in lymphoid tissues despite antiretroviral therapy, and may not necessarily develop drug resistance mutations, researchers reported in the January 27 online edition of Nature. While the existence of HIV reservoirs is well known, further characterizing the behavior of the virus in these sites could suggest new approaches to a cure.
Web Design and Development by