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When to Start ART?

New U.K. HIV Guidelines Cover When to Start ART, Treatment as Prevention, Pregnancy

The British HIV Association (BHIVA) has issued revised guidelines for antiretroviral therapy (ART) for adults and for pregnant women and prevention of mother-to-child HIV prevention. Comments are currently being accepted.alt

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Immediate ART during Early HIV Infection May Delay Disease Progression

People who started combination antiretroviral therapy (ART) within 6 months of HIV infection were less likely to experience large CD4 cell decreases or AIDS-related illnesses during follow-up, although viral load set point could not be evaluated, researchers reported in the December 15, 2011 Journal of Infectious Diseases.alt

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CASCADE Study Finds Benefit of ART Below CD4 Count of 500, But Not Above

Starting antiretroviral therapy (ART) at CD4 cell counts between 350 and 499 cells/mm3 predicted slower HIV disease progression among participants in the CASCADE cohort, investigators reported in the September 26, 2011, Archives of Internal Medicine. A similar benefit was not apparent, however, for those who started with 500-799 cells/mm3.alt

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New York City to Offer Antiretroviral Treatment to All People with HIV

New York City public health officials announced on World AIDS Day that they will begin offering antiretroviral therapy (ART) to all people diagnosed with HIV, regardless of CD4 T-cell count. The policy -- similar to one adopted by San Francisco in 2010 -- reflects a growing appreciation of the benefits of early treatment for both individual health and prevention of HIV transmission.alt

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IAS 2011: Randomized Trial Supports Earlier Treatment

The large HPTN 052 trial, best known for showing that early antiretroviral treatment prevents HIV transmission, also found virological, immunological, and clinical benefit to starting HIV treatment sooner.

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