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IAS 2013: New WHO Guidelines on HIV Treatment for Children Require Earlier Diagnosis

New World Health Organization (WHO) guidelines recommending antiretroviral treatment for all children with HIV under the age of 5, and treatment for all older children and adolescents with CD4 counts below 500 cells/mm3, will need to be backed up by efforts to greatly improve early infant diagnosis, together with development of easier-to-take antiretrovirals for children, pediatric experts told the 7th International AIDS Society conference (IAS 2013) on Monday.

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IAS 2013: WHO Issues New HIV Recommendations Calling For Earlier Antiretroviral Initiation

New HIV treatment guidelines by the World Health Organization (WHO) launched today at the 7th International AIDS Society Conference on HIV Pathogenesis, Treatment and Prevention in Kuala Lumpur recommend offering antiretroviral therapy to all HIV positive people at CD4 T-cell counts below 500 cells/mm3.

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Updated HIV Treatment Guidelines Include Stronger Recommendation for Acute Infection

On February 12, 2013, the U.S. Department of Health and Human Services antiretroviral therapy (ART) guidelines panel issued an update to the adult and adolescent HIV treatment guidelines. Among the key changes are additional information about the most recently approved antiretroviral agents and a recommendation that newly infected people with HIV should be offered combination ART.

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Updated Opportunistic Infection Guidelines Add Info on IRIS, Hepatitis, Drug Interactions

On May 7 the National Institutes of Health, Centers for Disease Control and Prevention, and HIV Medicine Association of the Infectious Diseases Society of Americaannounced the release of revised Guidelines for the Prevention and Treatment of Opportunistic Infections in HIV-Infected Adults and Adolescents, updating the previous version from 2009.

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Liver Toxicity Uncommon with Modern Antiretroviral Drugs, but Higher Risk for HIV/HCV Coinfected

Recently approved antiretroviral drugs are generally well-tolerated and seldom cause serious liver enzyme elevations, although protease inhibitors are somewhat more likely to do so, researchers reported in the November 28, 2012, advance online edition of AIDS. People with HIV/HCV coinfection are more likely to experience liver toxicity, however, and early hepatitis C treatment may improve the tolerability of HIV therapy.alt

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