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Anal & Cervical Cancer

IAS 2013: HPV Vaccination May Prevent Anal Cancer in Older Gay Men

A large number of infections with anal cancer-associated strains of human papillomavirus (HPV) among older gay men could be prevented with the use of HPV vaccines, Australian research reported at the recent 7th International AIDS Society Conference on HIV Pathogenesis, Treatment and Prevention (IAS 2013) in Kuala Lumpur. A related analysis showed that high-grade pre-cancerous cell changes were common but often resolved spontaneously.

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U.S. Cancer Rates Fall Overall, but Some HPV-associated Cancers Rise

Deaths due to all types of cancer combined decreased for men and women of all racial/ethnic groups in the U.S., according to a joint "Annual Report to the Nation," published in the January 7, 2013, advance edition of the Journal of the National Cancer Institute. Incidence of oral and anal cancer increased, however, leading the report authors to call for wider use of human papillomavirus (HPV) vaccines.

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HIV Is a Major Contributor to Increase in Anal Cancer among U.S. Men

Increased incidence of anal cancer during the past 3 decades among men in the U.S. has been strongly influenced by the HIV epidemic, although a similar association was not observed for women, researchers reported in the October 5, 2012, advance edition of the Journal of the National Cancer Institute. alt

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Topical Cidofovir Effective and Well-tolerated for Anal and Vulva Neoplasia

A topical formulation of the antiviral drug cidofovir (Vistide), best known as a treatment for cytomegalovirus (CMV), also appears effective for short-term treatment of high-grade anal and vulva cancer caused by human papillomavirus (HPV) in people with HIV, according to a report in the October 1, 2012, advance online edition of AIDS. alt

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ICAAC 2012: Progression of Anal Neoplasia is Common among Gay Men with HIV

Nearly 40% of HIV positive men with low-grade anal neoplasia may progress to high-grade neoplasia or anal cancer, according to a Spanish study presented at the 52nd Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC) this week in San Francisco. Younger age and shorter duration of HIV infection were risk factors for worsening disease.alt

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