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Human Papillomavirus (HPV)

Topical Cidofovir Effective and Well-tolerated for Anal and Vulva Neoplasia

A topical formulation of the antiviral drug cidofovir (Vistide), best known as a treatment for cytomegalovirus (CMV), also appears effective for short-term treatment of high-grade anal and vulva cancer caused by human papillomavirus (HPV) in people with HIV, according to a report in the October 1, 2012, advance online edition of AIDS. alt

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HIV Is a Major Contributor to Increase in Anal Cancer among U.S. Men

Increased incidence of anal cancer during the past 3 decades among men in the U.S. has been strongly influenced by the HIV epidemic, although a similar association was not observed for women, researchers reported in the October 5, 2012, advance edition of the Journal of the National Cancer Institute. alt

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AIDS 2012: Human Papillomavirus Doubles Risk of HIV infection

Pre-existing human papillomavirus (HPV) infection is associated with a 2-fold increase in the risk of HIV acquisition in women, and risk also rose for both heterosexual and gay/bisexual men, according to an 8-study review presented at the recent XIX International AIDS Conference (AIDS 2012) in Washington, DC, and published in the August 7, 2012, advance online edition of AIDS.alt

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ICAAC 2012: Progression of Anal Neoplasia is Common among Gay Men with HIV

Nearly 40% of HIV positive men with low-grade anal neoplasia may progress to high-grade neoplasia or anal cancer, according to a Spanish study presented at the 52nd Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC) this week in San Francisco. Younger age and shorter duration of HIV infection were risk factors for worsening disease.alt

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HPV Vaccine Provides Herd Immunity to Unvaccinated Women

The human papillomavirus (HPV) vaccine can offer protection to girls and young women who did not themselves undergo immunization, a phenomenon known as "herd immunity," according to a study published in the July 9, 2012, advance online edition of Pediatrics. Widespread immunity against high-risk altHPV types 16 and 18 may result in lower rates of cervical and anal cancer in years to come.

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