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Multidrug-Resistant Tuberculosis Treatment: 6 Drugs Better than 5

A regimen containing 6 drugs was more likely to cure multidrug-resistant tuberculosis (MDR-TB) than a regimen containing 5 drugs, a 9-country observational study has shown. The study also found that each active drug in the regimen increased the likelihood of a cure by 65%, and inclusion of pyrazinamide doubled the chance of curing MDR-TB, according to findings were published in the December 29 edition ofPLoS Medicine.

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WCLH 2015: Community Care Workers Boost TB Case Finding Among Hard-to-Reach Adults

Active case finding by community care workers is an effective tool for increasing tuberculosis (TB) case detection, according to 2 studies presented at the 46th Union World Conference on Lung Health held in December in Cape Town. Finding and diagnosing TB is the essential first step to closing the global gap in stopping TB.

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WCLH 2015: Death During MDR-TB Treatment More Likely in HIV+ and Underweight Patients

People living with HIV, those who are underweight, and those with more extensive drug resistance are more likely to die during treatment for multidrug-resistant tuberculosis (MDR-TB) in a 9-country study, according to a presentation at the 46th Union World Conference on Lung Health in Cape Town this month.

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10. Shorter Tuberculosis Prevention and Treatment

Studies presented this year showed that a 9-month treatment regimen cured more than 80% of people with multidrug-resistant tuberculosis (MDR-TB) in an observational study in Africa, while a 3-month regimen of isoniazid and pyrazinamide was as effective as 6 months of isoniazid alone at preventing the development of active tuberculosis disease in people with HIV.

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WCLH 2015: 9-Month Regimen Cures 82% of People with Multidrug-resistant TB in African Study

A 9-month standardized treatment regimen for multidrug-resistant tuberculosis (MDR-TB) cured 82% of people recruited to an observational study in Francophone Africa, according to a presentation at the 46th Union World Conference on Lung Health last week in Cape Town. The regimen showed similar effectiveness to the performance of 9-month MDR-TB treatment regimens in previous studies in Africa and Bangladesh, and with the exception of hearing loss, serious adverse events were rare.

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