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Cardiovascular Disease

FDA Review Finds No Link Between Abacavir Use and Heart Attacks

A meta-analysis by the U.S. Food and Drug Administration (FDA) offers further evidence that the NRTI abacavir (Ziagen, also in the Epzicom and Trizivir coformulations) is not significantly associated with an increased risk of myocardial infarction, according to a report published in the August 28, 2012, online edition of the Journal of Acquired Immune Deficiency Syndromes.alt

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ICAAC 2012: HIV+ People Have Heart Attacks Younger, Receive Later Care, Die More Often

People with HIV had heart attacks at a younger age than HIV negative individuals and were about 50% more likely to die after an acute myocardial infarction, according to a study presented this week at the 52nd Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC 2012) in San Francisco. A related analysis found that HIV positive people received coronary catheterization at a later stage, after they had more advanced heart damage.alt

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Starting ART below 350 CD4 Cells is Associated with Impaired Artery Function

HIV positive people who ever had a CD4 T-cell count below 350 cells/mm3 are more likely to have reduced flow-mediated dilation, a sign of blood vessel dysfunction linked to cardiovascular events such as heart attacks, according to a study described in the June 1, 2012, issue of AIDS. These findings suggest that starting antiretroviral treatment above this CD4 level may be beneficial.

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ICAAC Meeting Underway in San Francisco -- HIV, HCV, HPV, Flu, and More

The 52nd Interscience Conference on Antimicrobial Agents and Chemotherapy -- better known as ICAAC -- opened Sunday, September 9, at San Francisco's Moscone Center.alt

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HIV Infection Linked to Increased Stroke Risk

HIV positive people may have a higher risk of stroke independent of traditional risk factors, with the largest relative increase among younger people and women, according to study findings published in the May 10, 2012, advance online edition of the Journal of Acquired Immune Deficiency Syndromes.alt

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