Other Infections

Hospitalizations Due to Hepatitis A Declining in the U.S., CDC Study Finds

Rates of hospitalization related to hepatitis A virus (HAV) infection decreased in the U.S. from 2002 to 2011, possibly attributable to changing demographics and wider use of the hepatitis A vaccine, researchers reported in the September 29 edition of Hepatology.

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Hepatitis E Can Cause Rapid Liver Cirrhosis in People with HIV Who Have Low CD4 Cell Counts

Infection with hepatitis E virus (HEV) can cause rapid liver fibrosis in people with HIV who have low CD4 cell counts, case reports published in the April 10, 2013, online edition of Clinical Infectious Diseases show. Spanish investigators reported 2 instances of HEV infection in gay men with HIV who had severe immunosuppression. Treatment with ribavirin monotherapy led to normalization of liver function and temporary suppression of HEV replication. 

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Hepatitis A Immune Response Has Implications for Hepatitis C

Hepatitis A virus appears to evade immune defenses better than hepatitis C virus, even though it only causes short-term illness. Learning about differences between viral dynamics and immune response to HAV and HCV may offer information that can inform treatment.

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Hepatitis E Uncommon among HIV+ People, but May Cause Unexplained Liver Enzyme Elevations

Coinfection with hepatitis E virus (HEV) is not commonly seen in people with HIV, according to 2 recent reports, but it is a possibility to consider if a person has elevated liver enzymes not attributable to another apparent cause.alt

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Hepatitis A Vaccine Response Durable in People with HIV

People with well-controlled HIV infection respond well to hepatitis A vaccination, with 89% achieving an initial response and 85% still protected after 6-10 years.

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Ribavirin May Be Effective against Acute Hepatitis E

Ribavirin, a component of standard therapy for chronic hepatitis C, may also be an effective treatment for severe acute hepatitis E, French researchers reported in the July 14, 2011, Journal of Clinical Virology.alt

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HIV Positive People May Need Triple Dose of Hepatitis A Vaccine

People with HIV require 3 doses of hepatitis A virus (HAV) vaccine to achieve the same level of antibody protection that HIV negative people can get with 2 doses, according to a study presented at the 50th Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC 2010) last month in Boston. HAV antibody response was particularly weak among HIV positive men with a CD4 count below 200, all of whom needed the third vaccine booster dose.

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